Interaction of cytochrome c with cytochrome oxidase: two different docking scenarios
نویسندگان
چکیده
منابع مشابه
The Cytochrome C-cytochrome Oxidase Complex
In the preceding paper the oxidation of substrates by “indophenol oxidase” was demonstrated to be a joint action of cytochrome and cytochrome oxidase. It was further shown that with a given amount of oxidase the velocity of hydroquinone oxidation reached a maximum as the amount of added cytochrome was increased. The latter fact immediately suggested the probability that the rapid aerobic oxidat...
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Cytochrome c oxidase binds protonophore carbonyl cyanide 3-chlorophenylhydrazone (CCCP) with high affinity. There are 1.46 high-affinity binding sites per cytochrome c oxidase for CCCP with dissociation constant 2.7 x 10(-7) mol/l. The bond between the CCCP and cytochrome c oxidase accomplishes through the group on cytochrome c oxidase with pKa 6.64 and is based on the electrostatic interaction...
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In recent work on the reaction between oxygen and reduced cytochrome oxidase made by the method of Yonetani (1)) Gibson and Greenwood (2) found that the reaction is complex and that at least two spectroscopically distinguishable reactions must take place. The kinetic changes were interpreted in terms of a scheme proposed by Keilin and Hartree (3), according to which cytochrome oxidase preparati...
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In recent work on the reaction between oxygen and reduced cytochrome oxidase made by the method of Yonetani (1)) Gibson and Greenwood (2) found that the reaction is complex and that at least two spectroscopically distinguishable reactions must take place. The kinetic changes were interpreted in terms of a scheme proposed by Keilin and Hartree (3), according to which cytochrome oxidase preparati...
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Cell-sized polyelectrolyte capsules functionalized with a redox-driven proton pump protein were assembled for the first time. The interaction of polyelectrolyte microcapsules, fabricated by electrostatic layer-by-layer assembly, with cytochrome c oxidase molecules was investigated. We found that the cytochrome c oxidase retained its functionality, that the functionalized microcapsules interacti...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 2004
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2003.10.010